Some government ministers, including deputy premier Nick Clegg, are believed to favour a new form of press regulation underpinned by statute.
But NS boss Adrian Jeakings, who is also chief executive of Archant, has challenged Mr Clegg over the issue.
In the latest of a series of letters to the deputy premier, he reiterated that the industry was opposed to any form of statutory framework and called for a meeting to discuss its concerns.
Wrote Adrian: “The local press is vehemently opposed to any form of statutory involvement or ‘underpinning’ in the regulation of the press, however arms-length from government it might appear to be.
“No government could ever guarantee non-interference nor prevent its successors from tightening or extending statutory controls.”
“It is inconceivable that any statutory regime could be established to regulate just a small section of the popular national press, imposing special controls and penalties on some publications and not on others.
“In practice, hundreds of responsible national, regional and local newspapers and magazines would find themselves swept up into a costly and wholly unnecessary system of legal controls and constraints which would have an enormous impact on their freedom to publish in the UK.”
The letter was sent in response to Mr Clegg’s reply to an earlier letter by the NS president on 11 October challenging Mr Clegg over comments that the press behaved like “animals.”
In his reply, the DPM explained that his remarks, first made at the Liberal Democrats party conference last month, applied to the national rather than the regional press.
The NS is part of the Free Speech Network, an alliance of UK, European and overseas publishers who have come together to protect freedom of expression against any threats to introduce a statutory backstop to press regulation.